7MMTV

拉斐尔(Raphael N. Alolga)
副教授硕士生导师

电话:邮箱:[email protected]

办公室地址:江宁校区G354

研究领域:基于组学技术的植物疗法研究

招生方向:生药学

  • 个人简介
  • 教学与课程
  • 研究方向
  • 项目与成果
  • 奖励荣誉
  • 教材或专著
  • 课题组介绍
  • 在7MMTV 获得生药学博士学位,现任7MMTV 生药学系副教授。主要研究方向为药用植物在类风湿关节炎、炎症及代谢综合征等疾病中的治疗潜力。擅长应用组学技术开展中药材及其成品的质量评价与药效机制研究。

    担任African Journal of Traditional, Complementary and Alternative Medicines及Pharmacognosy Research编委。

    兼任Pharmacology & Toxicology of Natural Medicines副主编、Scientific African编辑,并曾担任MDPI旗下Pharmaceuticals客座编辑。

    担任多家知名同行评审期刊的审稿人,包括Food Chemistry、Industrial Crops and Products、Journal of Pharmacy and Pharmacology、Journal of Agriculture and Food Chemistry、Process Biochemistry以及Journal of the Science of Food and Agriculture等。


  • 用于治疗类风湿关节炎的xylopic acid缓释水凝胶的合成及其作用机制。

  • 1. Alolga, RN; Opoku-Damoah, Y; Alagpulinsa, DA; Huang, FQ; Ma, G.; Chavez Leon, M.A.S.C.; Kudzai, C.; Yin, X.; Ding, Y.  Metabolomic and transcriptomic analyses of the anti-Rheumatoid Arthritis potential of xylopic acid in a bioinspired lipoprotein nanoformulation. Biomaterials 2021, 268: 120482.

    2. Alolga, RN; Wang, SL; Ayensu, I; Nebeolisa, CS. Pharmacokinetics and in vitro liver microsomal enzyme metabolism of Xylopic acid. Journal of Pharmaceutical and Biomedical Analysis 2023, 224: 115200.

    3. Alolga, RN; Osae, R; Essilfie, G; Saalia, F.K.; Akaba, S; Chikari, F. Sonication, osmosonication and vacuum-assisted osmosonication pretreatment of Ghanaian garlic slices: Effect on physicochemical properties and quality characteristics. Food Chemistry. 2021, 343:128535.

    4. Alolga, RN; Osae, R; Apaliya, MT; Traore SI; Ahmed, MSA;Kwaw, E; Antiri, EA. Vacuum pressure combined with osmosonication as an innovative pre-drying technique for Ghanaian ginger: Evidence from the metabolome and quality characteristics of the dried product. Ultrasonics sonochemistry. 2021, 80: 105841.

    5. Alolga, RN; Osae, R;Traore SI; Onoja, V; Apaliya, MT; Kwaw, E; Huang, F.Q. Distinct metabolomes and quality characteristics of vacuum-assisted osmosonic-pretreated Curcuma longa L. rhizomes subjected to different drying methods. Industrial Crops and Products. 2022, 185: 115156.

    6. Liu, XH; Qi LW; Alolga RN*; Liu Q*. Implication of the hepatokine, fibrinogen-like protein 1 in liver diseases, metabolic disorders, and cancer: The need to harness its full potential. International Journal of Biological Sciences 2022, 18(1):292-300.

    7. Kesse, S; Xu, Y; Shi S; Jin S; Ullah S; Dai Y; He M; Zheng A; Xu F; Du Z; Alolga RN*; Peng J*. MDSC-targeted liposomal all-trans retinoic acid suppresses mMdscs and improves immunotherapy in HBV infection. Expert Opinion on Drug Delivery 2024, 21, 347-363.

    8. Alolga, RN; Ayensu I; Sosu, JX. Forced degradation studies, elucidation of degradation pathways and degradation kinetics of Xylopic acid via LC and LC-MS/MS analyses. Journal of Pharmaceutical Sciences 2023: S0022-3549(23)00008-4.

    9. Alolga RN, Wang SL, Qi LW, Zang H, Huang FQ.MALDI mass spectrometry imaging in targeted drug discovery and development: the pros, the cons, and prospects in global omics techniques. TrAC Trends in Analytical Chemistry 2024, 117860.

    10. Osae, R; Apaliya, MT; Kwaw, E; Chisepo, M.T.R; Naa Yarley, O.P.; Antiri, E.A.; Alolga, RN*. Drying techniques affect the quality and essential oil composition of Ghanaian ginger (Zingiber officinale Roscoe). Industrial Crops and Products. 2021, 172: 114048.


  • 1. 国家自然科学基金,NSFC(国际青年科学家基金项目,项目批准号:82150410450)。

    2. 科学技术部,MOST(外国专家重点项目计划,项目编号:WGXZ20221)。


  • 第四章:干血斑技术在治疗药物监测与毒理学中的应用。

    收录于《治疗药物监测与临床毒理学新进展》。

    编者:Prof. Seth Kwabena Amponsah 、Prof. Yashwant Pathak.

    出版社:Springer, USA.

    作者:拉斐尔、刘群、齐炼文。


    第九章:不同食品加工技术对黑孜然籽及其油脂成分的影响。

    收录于《黑孜然籽的生物化学、营养与治疗作用》。

    编者:Prof. Mariod Basit 、Prof. Gustav Mahunu.

    出版社:Elsevier, Netherlands.

    作者:Richard Osae, Maurice T. Apaliya, Newlove A. Afoakwa, Emmanuel Kwaw, 拉斐尔。


    第十三章:肝功能不全患者的药物处置。

    收录于《特殊人群的药物处置基础与临床应用》。

    编者:Prof. Seth Kwabena Amponsah 、 Prof. Yashwant Pathak.

    出版社:Wiley Publishing Company, New Jersey, USA.

    作者:Frieda A. Abilba, Jacob A. Ayembilla, 拉斐尔。